Good post! I agree with the sentiment for the most part but I think a little context is missing for “virtually every bio active compound has been screened against every drug target.” Our understanding of basic biology is rittled with garbage science that has kind of just stuck through with legacy; and enacted by the people in charge who got their phds before NGS existed. There are lots of drug targets we don’t know about, and lots of opportunity for more finely tuned tweaking of biology with gene therapies, cell therapies, advanced bio molecules etc.
Thanks Olek! Agreed on all fronts, there are big opportunities in exploring the vast space of possible bioactive compounds, and so much that can be done in identifying new targets or approaches. Great fodder for a future post. I might run a draft by you to make sure I'm not missing anything important!
Good post! I agree with the sentiment for the most part but I think a little context is missing for “virtually every bio active compound has been screened against every drug target.” Our understanding of basic biology is rittled with garbage science that has kind of just stuck through with legacy; and enacted by the people in charge who got their phds before NGS existed. There are lots of drug targets we don’t know about, and lots of opportunity for more finely tuned tweaking of biology with gene therapies, cell therapies, advanced bio molecules etc.
Thanks Olek! Agreed on all fronts, there are big opportunities in exploring the vast space of possible bioactive compounds, and so much that can be done in identifying new targets or approaches. Great fodder for a future post. I might run a draft by you to make sure I'm not missing anything important!